Includes bibliography

Preface -- Book I: The discovery of stress -- Precursors of the stress concept -- My first glimpse of stress -- How to question nature -- The birth of the G.A.S. -- Book II: The dissection of stress -- Why did we need a blueprint for the dissection? -- Inventory of assets: (a) the facts -- Inventory of assets: (b) the abstractions -- Inventory of assets: (c) materials and techniques -- How does one dissect a biologic mechanism? -- Results of the dissection -- Stress in a nutshell -- Stress and inflammation -- Synoptic view of the whole stress-mechanism -- Book III: The diseases of adaptation -- Diseases of the kidney, the heart, and the blood vessels -- Inflammatory diseases -- Other diseases -- "When scientists disagree" -- Book IV: Sketch for a unified theory -- The search for unification -- How could the stress concept lead to a more unified interpretation of biology and medicine? -- Apologia for teleologic thought in biology and medicine -- Book V: Implications and applications -- Medical implications of the stress concept -- Psychosomatic implications -- Philosophic implications -- The road ahead

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